Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity.
نویسندگان
چکیده
This work demonstrates a design strategy to optimize antimicrobial peptides with an ideal balance of minimal cytotoxicity, enhanced stability, potent cell penetration and effective antimicrobial activity, which hold great promise for the treatment of intracellular microbial infections and potentially systemic anti-infective therapy.
منابع مشابه
Designed filamentous cell penetrating peptides: probing supramolecular structure-dependent membrane activity and transfection efficiency.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 7 شماره
صفحات -
تاریخ انتشار 2015